Nasopharyngeal Carcinoma

A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.

Also Known As:

Carcinoma, Nasopharyngeal; Carcinomas, Nasopharyngeal; Nasopharyngeal Carcinomas

Neoplasms: 1324753
- Neoplasms by Site: 4
  - Head and Neck Neoplasms: 18117
    - Otorhinolaryngologic Neoplasms: 10
      - Pharyngeal Neoplasms: 357
        Nasopharyngeal Neoplasms: 1312
        Nasopharyngeal Carcinoma: 9722
- Neoplasms by Histologic Type: 2
  - Glandular and Epithelial Neoplasms: 439
    - Carcinoma: 141855
      - Nasopharyngeal Carcinoma: 9722
Stomatognathic Diseases: 705
- Pharyngeal Diseases: 21
  - Pharyngeal Neoplasms: 357
    - Nasopharyngeal Neoplasms: 1312
      - Nasopharyngeal Carcinoma: 9722
  - Nasopharyngeal Diseases: 15
    - Nasopharyngeal Neoplasms: 1312
      - Nasopharyngeal Carcinoma: 9722
Otorhinolaryngologic Diseases: 203
- Pharyngeal Diseases: 21
  - Pharyngeal Neoplasms: 357
    - Nasopharyngeal Neoplasms: 1312
      - Nasopharyngeal Carcinoma: 9722
  - Nasopharyngeal Diseases: 15
    - Nasopharyngeal Neoplasms: 1312
      - Nasopharyngeal Carcinoma: 9722
- Otorhinolaryngologic Neoplasms: 10
  - Pharyngeal Neoplasms: 357
    - Nasopharyngeal Neoplasms: 1312
      - Nasopharyngeal Carcinoma: 9722

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Therapy/Procedure